Unpacking the Federal Drug Price Reduction Struggle
How Political Rhetoric and Behind-the-Scenes Deal-Making Obscure Who Really Pays – or How Much
Our Mission
We connect researchers from across the University of Pennsylvania with a common mission: to improve health and health care by catalyzing collaborative, multidisciplinary research that influences policy and practice.
Featured Research Updates
Our work addresses some of the most pressing health and health care challenges facing our nation today.
Patients Face New Barriers for GLP-1 Drugs Like Wegovy and Ozempic
Even With Lower Prices, Medicare, Medicaid, and Other Insurers Tighten Coverage for Drugs Like Mounjaro and Zepbound Using Prior Authorization and Other Tools
America’s Kids Can’t Outrun a Broken Food System
Guidelines Matter, but Lasting Health Requires Investment in Better Food, More Activity, and More Targeted Tools From Medicaid and SNAP
Dancing Students Toward Health Care Career Opportunities
A Wharton–Netter Center Collaboration Uses Experiential Learning to Build a Health Care Workforce Pipeline
Heart Failure Patients May Get Sicker When the Rent Is Too High
Cheaper Housing Could be a Way to Lower Hospitalizations Among Medicaid Patients with Heart Failure
When Nurses Strike, It’s a Warning About Patient Safety
An LDI Expert Connects Nurse Wellbeing and Staffing to Patient Safety Outcomes
Impact Report
Our commitment to driving positive change through transformative research powered a series of standout achievements in 2025. Explore how we turned evidence into action to shape smarter health policy.
Upcoming Events
In-Person Event
Research Seminar with Riley League, PhD
Fragmented Insurance and Billing Frictions: Understanding Denied Health Insurance Claims
Open to Penn Affiliates
In-Person Event
Policy Seminar with Liz Fowler, PhD, JD
Health Policy at a Crossroads: Protecting Progress, Building for the Future
Open to Penn affiliates
Our Experts
Our 500+ Fellows are national experts and thought leaders who bridge all of Penn’s schools, the University of Pennsylvania Health System, and the Children’s Hospital of Philadelphia.
Gabriela Khazanov, PhD
- Research Associate, Center for Mental Health , Perelman School of Medicine
- Research Psychologist, Center of Excellence for Substance Addiction Treatment and Education (CESATE)
Christina Parisi, PhD, MPH
- Postdoctoral Fellow, Penn Center for Mental Health , Perelman School of Medicine
MaryAnne (Marty) Peifer, MD, MSIS
- Professor, Family Medicine and Community Health , Perelman School of Medicine
Ernesto Ulloa-Pérez, PhD
- Postdoctoral Fellow, Department of Biostatistics, Epidemiology and Informatics , Perelman School of Medicine
Alexis Boulter, MD
- Clinical Fellow , Children’s Hospital of Philadelphia
- Instructor, Pediatrics , Perelman School of Medicine
Wade Berrettini, MD, PhD
- Emeritus Professor, Psychiatry , Perelman School of Medicine
Anna Wexler, PhD
- Assistant Professor, Medical Ethics & Health Policy , Perelman School of Medicine
Maria Altieri, MD, MS
- Assistant Professor, Surgery , Perelman School of Medicine
What We Do
As Penn’s hub for health care delivery, health policy, and population health, we connect and amplify over 500 Fellows across the University, and train the next generation of researchers.
Fast Facts
$160M+
Awarded in External Grant Funding
11,300+
Journal Articles Published (2020–2024)
$400K+
Awarded in Research Grants from LDI