Penn LDI Research Program on Care for Medically Complex Patients

Supporting research to generate rigorous, timely new evidence informing ways to improve the management of polychronic conditions and health outcomes for patients, particularly those with chronic kidney disease.

Penn LDI has launched a new program to support research that will transform management of polychronic conditions and health outcomes for patients, particularly those with chronic kidney disease. The Penn LDI Research Program on Care for Medically Complex Patients will fund rapid-turnaround high-impact research projects that will have a meaningful and measurable impact on care and support the widespread dissemination of research results to relevant stakeholders, thereby influencing policy and care delivery. We anticipate funding up to two research projects, each lasting up to 15 months. This program is made possible by a generous gift from Monogram Health.

See Request for Proposals

Eligibility

Proposals must be led by an LDI Senior Fellow. Penn faculty without an LDI affiliation and LDI Associate Fellows may participate as co-investigators. Non-Penn collaborators are permitted with justification.

Application Process and Timeline

The Advisory Committee will select up to two projects, each lasting 15 months. Project budgets may not exceed $175,000. Faculty salaries and benefits may be included only with strong justification and may not exceed 20% of the award. Conference travel, equipment, or indirect costs are not allowed.

Applications will be due Monday, September 28, 2026, at 11:59 p.m. ET. Funding decisions are expected to be made in October 2026. IRB approval is required before funds are released. PIs must submit their projects to the IRB for approval upon notice of funding. Selected projects are expected to start by January 2027.

FAQ

Can an investigator mention relevant data they have access to in their proposal?

Yes, we recommend receiving a letter of support from the data owner to use data for your specific project.

Can investigator teams have more than one Principal Investigator?

Yes, teams can have up to two Principal Investigators.

Does the ban on indirect costs also apply to sub-awards for faculty co-investigators at other universities?

Yes.

Are graduate students or nurses working on projects subject to the 20% salary and benefits limit?

No, the 20% salary and benefits limit applies to only faculty (including research track/non-standing), not staff.

Are hyperlinks to online data (ie. video material) allowed to be included in the application?

Yes, applicants are allowed to link to online data in their application.

Are investigators allowed to include publication costs and/or software in the budget?

Yes, but if the grant pays 100% for the software, then it should be justified within the proposal.

Have a question?

Please email Caleb Hearn.


Advisory & Grant Review Committee

Yuvaram Reddy

Yuvaram Reddy, MBBS, MPH

Assistant Professor, Renal-Electrolyte & Hypertension, Perelman School of Medicine

Sandra (Sandi) Amaral, MD, MHS

Associate Professor, Pediatrics and Epidemiology, Perelman School of Medicine

Colonial Penn Center

LDI Executive Director

Shaminder Gupta, MD

Chief Medical Officer, Monogram Health

Greg Hicks, MBA

Chief Human Resources Officer, Monogram Health

Adam S. Wilk, PhD

Associate Professor, Surgery & Public Health, Indiana University

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