From 2003 to 2019, Ralph Muller served as Chief Executive Officer of the University of Pennsylvania Health System‚ a world-renowned academic medical center-based health system with 38,000 staff caring for more than 5 million patients annually. Prior to joining UPHS, he was, from 1985 to 2001, the President of The University of Chicago Hospitals and Health System. In 2001-2002, he was a Visiting Fellow at the Kings Fund in London, U.K.
In 1985-86 Mr. Muller also served as the Deputy Dean of the Division of the Biological Sciences at the Pritzker School of Medicine at the University of Chicago. Previously, he had been Budget Director at the University.
Before joining the University of Chicago, Mr. Muller held senior positions with the Commonwealth of Massachusetts, serving as Deputy Commissioner of the Massachusetts Department of Public Welfare, where he was the chief operating officer responsible for the state's major welfare programs, including Medicaid.
Mr. Muller received his bachelor's degree in economics from Syracuse University and a master's degree in government from Harvard University.
Mr. Muller has served on the boards of several national health care organizations. He is a Director of the National Committee for Quality Assurance (NCQA),Vizient and ECRI. He has served as Commissioner on the Medicare Payment Advisory Commission (MedPAC), Commissioner of The Joint Commission (TJC), Chairman of the Association of American Medical Colleges (AAMC), Chairman of the Council of Teaching Hospitals and Health Systems (COTH), Chairman of the University HealthSystem Consortium (UHC) and Chairman of the National Opinion Research Center at the University of Chicago (NORC).
He is an elected Member of the National Academies of Medicine, and a Fellow of the American Association for the Advancement of Science (AAAS).