George L. Anesi, MD, MSCE, MBE, is an Instructor of Medicine at the University of Pennsylvania Perelman School of Medicine and an Attending Physician in Pulmonary and Critical Care Medicine at the Hospital of the University of Pennsylvania. He has advanced training in health services research, clinical epidemiology, high-risk pathogen and disaster preparedness, biomedical ethics, and global health. His research interests focus on the evaluation of critical care and acute care resources during times of strain to the system, including situations of dynamic strain (i.e., random variation in demand, seasonal trends, epidemics, and disasters) and fixed strain (i.e., critical illness in resource-limited settings domestically and globally). Dr. Anesi received his undergraduate degree from the University of Chicago and his MD from Case Western Reserve University School of Medicine. He completed his internal medicine residency at Massachusetts General Hospital and his fellowship in pulmonary and critical care medicine at Penn. He also holds masters degrees in clinical epidemiology (Penn) and bioethics (Case Western). At Penn, Dr. Anesi sees patients in the medical intensive care unit and on the rapid response service, and serves as the Director of the Medical Critical Care Bioresponse Team where he is responsible for preparedness for the treatment of patients with emerging and high-risk pathogens in the Special Treatment Unit.