Unpacking the Federal Drug Price Reduction Struggle
How Political Rhetoric and Behind-the-Scenes Deal-Making Obscure Who Really Pays – or How Much
As the new year begins, we look back at a dozen of the most significant LDI news stories published in 2025. Together, they capture many of the most urgent challenges facing U.S. health care policy, including the destructive effects of the new administration’s anti-science health policies, the accelerating and disruptive rise of artificial intelligence across the health care delivery system, the dismantling of the nation’s vaccination infrastructure, the continuing harms of health care corporatization, and a growing retreat from documenting and addressing health disparities.

The Price of Obamacare Subsidies Loss: Millions Uninsured, Thousands at Greater Risk
Penn LDI/Tradeoffs Panel Discussion Eyes Impact of December Congressional Cutoff

After Fifteen Years, is Value-Based Care Succeeding?
Penn LDI Debates the Pros and Cons of Payment Reform

Black Maternity Patients More Likely to Experience Clinical Communications Failures
New Penn LDI Study Is Based on Hospital Incident Reports Rather Than Electronic Health Records

Shutting Down Federal Support for LGBTQ+ Health Care and Research
Penn Medicine Health Equity Week Panel Eyes an Extraordinary Unraveling

Penn Experts Warn New Vaccine Policy Could Undermine Public Health
Offit and Buttenheim Criticize HHS Placebo Trial Mandate as Unethical, Misleading, and a Threat to Vaccine Confidence

How Corporatization Continues to Change U.S. Health Care
Penn LDI Virtual Seminar Featured Top Experts Analyzing the Issues

In the Loop or On the Loop: The Conundrum of AI Clinical Decision Support
2025 Penn Nudges in Health Care Symposium Focuses on the Human-Machine Interface

National Academy of Medicine Issues Code of Conduct to Guide Health Care’s AI Revolution
One of the Authors, Penn’s Kevin B. Johnson, Explains the Principles It Sets Out

AI Pushes Medical Schools Into New Era, but Are They Prepared?
Experts at Penn LDI Panel Call for Rapid Training of Students and Faculty

Why Population Health Programs are Such a Challenge for Health Systems
An Analysis of Penn Medicine Healthy Heart Program Provides Insights

Using Tax and Labor Policies to Improve Population Health
A Penn LDI and Opportunity for Health Lab Virtual Seminar Explores Economic Assistance Programs

New APHA Book Warns Social Systems Are Driving Deepening Health Inequities
Penn LDI’s Antonia Villarruel and 10 Other Authors Map Social Determinants Across Multiple Racial and Ethnic Groups

How Political Rhetoric and Behind-the-Scenes Deal-Making Obscure Who Really Pays – or How Much
Even With Lower Prices, Medicare, Medicaid, and Other Insurers Tighten Coverage for Drugs Like Mounjaro and Zepbound Using Prior Authorization and Other Tools
Guidelines Matter, but Lasting Health Requires Investment in Better Food, More Activity, and More Targeted Tools From Medicaid and SNAP
A Wharton–Netter Center Collaboration Uses Experiential Learning to Build a Health Care Workforce Pipeline
Cheaper Housing Could be a Way to Lower Hospitalizations Among Medicaid Patients with Heart Failure
An LDI Expert Connects Nurse Wellbeing and Staffing to Patient Safety Outcomes