In Foundations and Trends in Technology, Information, and Operations Management, Hummy Song and Anita Tucker present a framework for performance improvement in health care organizations. Performance improvement is an important organizational capability that is essential for health care organizations to achieve excellence on the three components of the Triple Aim: patient experience, health, and cost. The authors’ model, called the Model of Transformational Performance Improvement, takes a system-level approach to performance improvement and comprises six key components. These components are: 1.) Determining and communicating a system-level goal; 2.) Developing and using system-level performance measures; 3.) Understanding and managing interdependencies; 4.) Selecting a portfolio of projects aligned with system-level goals; 5.) Creating an organizational engine for improvement; and 6.) Implementing, spreading, and sustaining improvements. Additionally, the authors review the operations management literature on performance improvement with a special focus on operations management tools and principles that may help with successful implementation of these six components. The authors conclude that, while many opportunities for future research exist, this model may inform the research of operations management scholars and equip clinicians with techniques to improve performance in health care organizations.