Adoption and Diffusion

How the latest clinical, technological, and policy advances are incorporated into clinical practice and health care delivery.

Do Physician Incentives Increase Patient Medication Adherence?

Aug. 1, 2020

Edward Kong, John Beshears, David Laibson, Brigitte Madrian, Kevin Volpp, George Loewenstein, Jonathan Kolstad, James J. Choi

Abstract [from journal]

Objective: To test the effectiveness of physician incentives for increasing patient medication adherence in three drug classes: diabetes medication, antihypertensives, and statins.

Data sources: Pharmacy and medical claims from a large Medicare Advantage Prescription Drug Plan from January 2011 to December 2012.

Study design: We conducted a randomized experiment (911 primary care practices and 8,935 nonadherent patients) to test the effect of paying physicians for


Hospital Financial Incentives to Improve Care After Opioid Overdose

Jan. 6, 2020

Two patients are treated for opioid overdose at two different hospitals, just a few miles apart. The first hospital provides life-saving treatment to reverse the overdose and watches the patient for an hour, discharging them when deemed “medically stable.” The second hospital also provides life-saving treatment but then offers counseling, medication to prevent recurrent overdose and treat opioid withdrawal, and assistance navigating to outpatient treatment for the next day.

National Trends in Utilization and 1-Year Outcomes with Transplantation of HCV-Viremic Kidneys

Peter P. Reese, MD, MSCE
Sep. 12, 2019

Vishnu S. Potluri, David S. Goldberg, Sumit Mohan, Roy D. Bloom, Deirdre Sawinski, Peter L. Abt, Emily A. Blumberg, Chirag R. Parikh, James Sharpe, K. Rajender Reddy, Miklos Z. Molnar, Meghan Sise, Peter P. Reese

Abstract [from journal]

Background: Recent pilot trials have demonstrated the safety of transplanting HCV-viremic kidneys into HCV-seronegative recipients. However, it remains unclear if allograft function is impacted by donor HCV-viremia or recipient HCV-serostatus.

Methods: We used national United States registry data to examine trends in HCV-viremic kidney use between 4/1/2015 and 3/31/2019. We applied advanced matching methods to compare eGFR for similar kidneys transplanted into highly similar recipients of kidney transplants.