Joseph Ladines-Lim, MD, PhD, is an infectious diseases fellow and a student in the Master of Science in Clinical Epidemiology program at the University of Pennsylvania. His current research is twofold: evaluating the impact of local and national policy on key outcome metrics within diagnostic and antimicrobial stewardship, and examining clinical outcomes of difficult-to-treat infections using Staphylococcus aureus as a model organism. His work incorporates patient characteristics, hospital data, and organism-level data, such as antibiotic susceptibilities and whole-genome sequencing.
He has a particular interest in studying these issues in vulnerable populations, such as individuals with substance use disorder, and determining which treatment regimens have the highest real-world effectiveness. Previously, he has worked on a wide range of projects, including basic science research in enzyme engineering and biophysics; global health fieldwork on the Zika virus in Brazil and tuberculosis in South Africa; and health services research on antimicrobial appropriateness using public surveillance data from the Centers for Disease Control and Prevention.
Ladines-Lim earned his PhD in Chemical Engineering from the Massachusetts Institute of Technology in 2015, where he was a National Science Foundation Graduate Research Fellow, and his MD from Yale School of Medicine in 2020. He completed combined internal medicine–pediatrics residency training at the University of Michigan in 2024.