Penn LDI has launched a new initiative to support research that will transform the health care delivery for patients with chronic kidney disease (CKD), with a particular focus on addressing disparities in care, including structural barriers and racial inequities. The Penn LDI Research Initiative on Improving Management of Chronic Kidney Disease is a research initiative to fund rapid-turnaround high- impact research projects that will have a meaningful and measurable impact on improving the delivery of care for individuals with CKD. We anticipate funding up to five research projects over three years (through two Requests for Proposals). This program is made possible by a generous gift from Monogram Health.

Research Initiative Director

Peter Reese

Peter Reese, MD, PhD

Director, Research Initiative on Improving Management of Chronic Kidney Disease, Penn LDI; Professor, Medicine and Epidemiology, Perelman School of Medicine

2022 Request for Proposals

We are seeking proposals for research projects that will generate rigorous new evidence to advance the U.S. health care system’s capacity to effectively identify, manage, and improve outcomes of patients with CKD.  Each project can last up to two years and total project budgets may be up to $350,000 (across all years).


Proposals must be led by an LDI Senior Fellow. See more information on how to become an LDI Senior Fellow. University of Pennsylvania faculty without LDI affiliations and LDI Associate Fellows are permitted to be co-investigators on proposals. Investigators outside Penn are permitted to be co-investigators if sufficient justification is provided for why their expertise is needed.

For investigators without substantial expertise in CKD, LDI may be able to provide connections to collaborators with that CKD expertise. 

Application Process and Timeline

The Grant Review Committee will select two to three projects, each lasting one to two years. Applications are due Tuesday, January 31, 2023, at 11:59 p.m. ET.

We plan to notify successful applicants of funding by Mid-February, 2023, with funding to begin Monday, March 6, 2023.

2023 Grant Review Committee


Are investigators allowed to request preliminary data from Monogram Health?

Yes, please email with any preliminary data requests.

Will investigators be able to recruit patients enrolled in Monogram Health as study participants?

Yes. Please email for more information.

Will investigators be able to recruit clinicians providing care to patients enrolled in Monogram Health?

Yes. Please email  for more information.

If you have questions about the Monogram Health dataset that are project specific and would like to discuss with Monogram Health’s Epidemiologist:

Please email for more information.

Can an investigator mention relevant data they have access to in their proposal?

Yes, we recommend receiving a letter of support from the data owner to use data for your specific project.

Can investigator teams have more than one Principal Investigator?

Yes, teams can have up to two Principal Investigators.

Does the ban on indirect costs also apply to subawards for faculty co-investigators at other universities?


Are graduate students or nurses working on projects subject to the 30% salary and benefits limit?

No, the 30% salary and benefits limit only applies to faculty.

Are hyperlinks to online data (ie. video material) allowed to be included in the application?

Yes, applicants are allowed to link to online data in their application.

Have a question?

Please email

Q&A Webinar

Penn LDI hosted an informational webinar about the initiative on December 14, 2022. See a recording below.

Advisory Committee

Rachel M. Werner

Rachel M. Werner, MD, PhD

Executive Director, Penn LDI

Peter Reese, MD, PhD

Director, Research Initiative on Improving Management of Chronic Kidney Disease, Penn LDI

Mark Neuman

Mark Neuman, MD, MSc

Director, Research Partnerships, Penn LDI

Manjula Tamura, MD MPH

Professor of Medicine (Nephrology), Stanford University

Shaminder Gupta, MD

Chief Medical Officer, Monogram Health

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