James Lewis, MD, MSCE, is Professor of Medicine and Epidemiology, Senior Scholar in the Center for Clinical Epidemiology and Biostatistics, and Associate Director of the Inflammatory Bowel Disease program at the University of Pennsylvania’s Perelman School of Medicine in Philadelphia, Pennsylvania. Dr. Lewis has been actively involved in clinical research related to inflammatory bowel diseases, medication safety, and optimizing medical therapies for nearly 20 years. More recently, he has focused on the impact of diet on the gut microbiome and the course of inflammatory bowel disease. His work has been funded by the NIH, AHRQ, PCORI, and numerous foundations and corporate sponsors. He is currently in leadership roles for 3 clinical trials for treatment of inflammatory bowel disease using nutritional interventions and one using a microbiome directed intervention. Dr. Lewis previously served as the Chair of the National Scientific Advisory Committee and a member of the National Board of the Crohn’s & Colitis Foundation. He is currently the lead scientist for the Foundation’s IBD Plexus Research Collaborative and an Associate Editor for Inflammatory Bowel Diseases.