Lindsey Fernandez, PhD

Lindsey Fernandez, PhD is a Postdoctoral Research Associate in the Department of Bioengineering and the Penn Institute for Computational Science at the School of Engineering and Applied Sciences. Dr. Fernandez has studied the mechanistic underpinnings of cancer progression, anti-tumor immunity, and therapeutic resistance through advanced systems biology methods, including multiscale modeling, agent-based modeling, neural networks, and quantitative systems pharmacology. Her research has focused on identifying the mechanisms by which exosomes and micro-RNAs modulate tumor-immune cell interaction, which contribute to patient-to-patient differences in therapeutic effectiveness, and on developing mechanistic, personalized, and predictive models of combination therapies. Dr. Fernandez hopes to expand advanced computational modeling research focus from targeted therapies to more affordable and accessible combination therapies. Dr. Fernandez received her PhD from the University of Pennsylvania in 2021 and currently serves as Co-President for the Penn Science Policy and Diplomacy Group (PSPDG).