These Patients Have Nothing Else. Should That Be Enough for FDA Drug Approval?
Despite Streamlined Processes, FDA’s Role in Rare-Disease Drug Development Draws Continued Scrutiny
Research & Policy Updates
New Model Predicts Stimulant Overdose Risk Among Medicaid Patients
LDI Fellows Used Medicaid Data to Identify Individuals at Highest Risk for Cocaine- and Methamphetamine-Related Overdoses, Paving the Way for Targeted Prevention
Penn CHIBE Retreat Eyes New AI Tools to Get Evidence to Policymakers
More Focused and Comprehensive Large Language Model Chatbots Envisioned
Medicare Advantage Narrows Some Racial Gaps in Preventive Care, but Disparities Persist
Medicare Advantage Modestly Cut Black–White Disparities in Chronic Disease Prevention Compared to Traditional Medicare, but Care Gaps Remain for Latinx Populations
The Unseen Fallout of Abortion Bans
How Threatened Reproductive Rights Pushed More Pennsylvanians Toward Sterilization
Hospitals Rarely Use Z Codes to Document Patients’ Social Risks
Billing Codes That Flag Food, Job, or Housing Insecurity in Medical Records are Underused for the Sickest Medicare Patients
Cash Transfers and Healthy Birth Outcomes
Promising New Evidence and What’s Next
Diagnostic Biomarker Tests are ‘Deconstructing Dementia’
Precision Diagnostics Give Patients Clearer Answers About What Drives Cognitive Impairment
Parents Need Time, Not Deadlines, After Fetal Diagnoses
Abortion Restrictions Can Backfire, Pushing Families to End Pregnancies
NIH on the Brink: How to Fund Medical Breakthroughs in the Trump–Kennedy Era
With Drastic Cuts on the Table, What’s the Best Way To Fund Medical Innovation – NIH Grants, Prizes, or Bold New Models?
Why Population Health Programs are Such a Challenge for Health Systems
An Analysis of Penn Medicine Healthy Heart Program Provides Insights
Black Life Expectancy Shows Sharp Geographic Divide: Cities Gained, While Midwest and Rural Areas Fell Back
From 1990 to 2019, Black Life Expectancy Rose Most in Major Metros and the Northeast—but Gains Stalled or Reversed in Rural Areas and the Midwest, Especially for Younger Adults