Kevin B. Mahoney is chief executive officer of the University of Pennsylvania Health System, a pillar of the Penn Medicine enterprise. He leads health system operations, spanning six hospitals, 11 multispecialty centers and hundreds of outpatient facilities in Pennsylvania, Delaware and New Jersey.
Penn Medicine consists of the University of Pennsylvania Health System and the Perelman School of Medicine. Together, they form one of the world’s leading—and America’s oldest—academic medical centers dedicated to the related missions of medical education, biomedical research, and excellence in patient care.
Mahoney joined Penn Medicine in 1996, holding leadership posts for nearly three decades. Before his appointment as CEO in July 2019, he served as executive vice president and chief administrative officer of the University of Pennsylvania Health System and as executive vice dean of the Perelman School of Medicine.
Across Penn Medicine, Mahoney has led transformational initiatives focused on improving patient experience and care efficiency in treatment settings. Most recently, he oversaw the creation of the Pavilion, a 1.5-million-square-foot, future-forward hospital. He also directed a yearslong project to unite the health system’s hospitals, clinics, and home care programs under one shared electronic health records platform.
An advocate for access and equity, Mahoney launched a partnership with the Wharton School of the University of Pennsylvania to provide investment funds to early-stage businesses focused on strengthening the social determinants of health in underserved populations. Beyond medicine, Mahoney has been a driving force to integrate Penn Medicine discoveries into the landscape of “Cellicon Valley,” an emerging gene and cell therapy innovation cluster in Philadelphia.
Mahoney has contributed to The New England Journal of Medicine, the Journal of the American Medical Association and The Philadelphia Inquirer, offering perspectives on health equity, access to quality care, social justice and more. In 2022, he was named one of the “100 Most Influential People in Health Care” by Modern Healthcare.
A graduate of Millersville State College in Millersville, Pennsylvania, Mahoney earned a bachelor’s degree in economics. He also holds an MBA and a doctorate from the Fox School of Business at Temple University in Philadelphia.